To evaluate the consequences of reduced Polβ levels on adult olfactory neurogenesis in an AD mouse model, we administered the DNA precursor BrdU to WT, Polβ+/−, 3xTgAD, and 3xTgAD/Polβ+/− mice (14‐month‐old mice littermates) (Fig. 2A). Here, POLB is linked to Alzheimer disease.