Whereas the fraction of γδ T cells positive for IFN-γ after stimulation with IL-2+IL-15+zoledronate was comparable between healthy donors and AML patients, IL-2+zoledronate stimulation gave rise to more IFN-γ positive γδ T cells when derived from AML patients relative to healthy donors. The gene discussed is IL2; the disease is acute myeloid leukemia.