PLAT and ischemic stroke: With the approval of idarucizumab, a novel monoclonal antibody fragment with a high potency to reverse the anticoagulant effects of dabigatran within minutes [5, 6], the question arose if recombinant tissue plasminogen activator (rt-PA) could be used after reversal of dabigatran with idarucizumab in individuals with newly occurring ischemic stroke.