MAP7high patients with CN-AML were more likely to have a higher expression of ERG, WT1, DNMT3B, DNMT3A, MAPKBP1, ITPR2 and ATP1B1 mutations than MAP7low patients (P = 0.0004, P < 0.0001, P < 0.0001, P = 0.03, P = 0.01, P = 0.005, and P < 0.001, respectively). The gene discussed is DNMT3A; the disease is acute myeloid leukemia.