In this cohort, MAP7high patients with CN-AML were more likely to have higher expressions of ERG, WT1, DNMT3B, DNMT3A, ITPR2, MAPKBP1 and ATP1B1 (P < 0.001, P < 0.001, P < 0.001, P = 0.02, P < 0.001, P < 0.001, and P < 0.001, respectively) and lower expression of LEF1 (P = 0.001) compared with MAP7low patients (Supplementary Table 1). Here, LEF1 is linked to acute myeloid leukemia.