XRCC5 and malignant colon neoplasm: In one study, a novel antibody (7B7) directed against the Ku70/Ku80 heterodimer was confirmed to block invasion in pancreatic and lung cancer cells.12 Ku80 was found to be involved in the migration process of thymosin beta4-regulated colon cancer cells.13 Thus, the relationship between Ku80 and cancer cell invasion needs further investigation.