However, the analysis of 42 human primary ovarian cancer specimens and 10 normal ovarian tissues revealed that SDS22 mRNA expression was only slightly downregulated in ovarian cancer tissues (data not shown), and a survey of the TCGA database indicated that SDS22 mRNA levels were not associated with the overall survival of ovarian cancer patients (Supplementary Table S2a). This evidence concerns the gene PPP1R7 and ovarian cancer.