KRAS and renal carcinoma: However, these findings contradict a previous report that miR-134 functions as a tumor suppressor by targeting K-Ras in renal carcinoma cells.15 Analysis of data from the TCGA database indicated that higher expression levels of miR-134 were associated with decreased median overall survival in 10 types of cancers, but were associated with increased median overall survival in three types of cancers (Supplementary Table S2a).