However, these findings contradict a previous report that miR-134 functions as a tumor suppressor by targeting K-Ras in renal carcinoma cells.15 Analysis of data from the TCGA database indicated that higher expression levels of miR-134 were associated with decreased median overall survival in 10 types of cancers, but were associated with increased median overall survival in three types of cancers (Supplementary Table S2a). The gene discussed is KRAS; the disease is cancer.