FOSL1 and ovarian carcinoma: We examined miR-134 and Fra-1 expression in 42 human primary ovarian cancer specimens and 10 normal ovarian tissues.44 Real-time RT-PCR analysis demonstrated that miR-134 and Fra-1 mRNA expression was increased in human ovarian tumor tissues compared with normal ovarian tissues (Figures 7a and b), and Fra-1 expression levels were positively correlated with miR-134 expression levels (Figure 7c).