In a study on colorectal cancer, researchers found that miR-149 was downregulated in tissues of colorectal cancer and inversely correlated with expression level of FOXM1 which was regulated by miR-149 in post-transcriptional level, low miR-149 expression was observed to be significantly associated with lymph node or distant metastasis and advanced TNM. Here, FOXM1 is linked to colorectal cancer.