The corresponding KRAS single amino acid missense mutations are located at codons 12 or 13 for exon 2, codons 59 or 61 for exon 3, and codons 117 or 146 for exon 4, with G12D (13.1% prevalence), G12V (11.6%), and G13D (8.1%) being most prevalent in colorectal cancer. The gene discussed is KRAS; the disease is colorectal cancer.