There was significant heterogeneity (P = 0.01, I2 = 67%), and a random-effects model showed the CD147 positive expression rate in prostate cancer tissues was higher than that in normal prostate tissues (OR = 26.93, 95% CI = 7.95–91.20, P < 0.00001) (Fig 2A). The gene discussed is BSG; the disease is prostate carcinoma.