The regression model for the left hippocampus was significant [F(4,68) = 3.357, p = 0.014, R2 = 0.165, R2adjusted = 0.116], revealing a main effect of COMT genotype (p = 0.020) and a significant interaction between COMT genotype and childhood trauma (p = 0.012) on inhibition-related left hippocampal activation. The gene discussed is COMT; the disease is injury.