Likewise, expression of lin28b, in this case from the haemopoeitic-ubiquitous vav promoter, leads to a PTCL-like disease in mice, although links to human disease are tenuous, with Lin28b reported as being overexpressed by on average 7.5-fold in PTCL, NOS (n = 50) [30]. This evidence concerns the gene LIN28B and mature T-cell and NK-cell non-Hodgkin lymphoma.