Other tumor suppressors, such as Dipeptidyl peptidase 4 (DPPIV), Pigment epithelium-derived factor (PEDF) and SerpinB5 were also upregulated in the secretome of T24shPFN1 cells, (30.3, 13.6 and 9.7-fold, respectively). This evidence concerns the gene SERPINB5 and neoplasm.