In a previous study, Urbani et al. selected MYCN non-amplified neuroblastoma cells resistant to etoposide and they identified by proteomic analysis some potential markers of drug resistance such as Hsp27, beta-galactoside soluble lectin binding protein, vimentin, heterogeneous nuclear ribonucleoprotein K and peroxiredoxin [23]. The gene discussed is VIM; the disease is neuroblastoma.