PDE4D and posterior cortical atrophy: Notably, expression of all long PDE4D isoforms including PDE4D5 and PDE4D7 appears to decrease during PCa progression (see Figure 1 and Supplementary Figures S2-S3), while expression of the super-short PDE4D isoforms PDE4D1 and PDE4D2 seemed to be affected to a lesser extent.