CD44 and cancer: Our flow cytometry results demonstrated that treatment of the two cell lines with Asp-UA could reduce the expression of integrin α6, β1, CD44 (Figure 4A and Figure 4B) and promote the expression of E-cadherin in MCF-7 cells (Figure 5C and Figure 5F), implying that integrin α6β1/CD44/E-cadherin on MCF-7 and MDA-MB-231 surface were partly responsible for the mechanism of Asp-UA on cancer metastasis prevention.