Previous research studies on CACNA1C primarily focused on the genetic effect of another SNP, rs1006737, which GWASs found to be associated with schizophrenia in European populations6, 7, but which has a much lower minor allele frequency (MAF) in East Asian populations (http://hapmap.ncbi.nlm.nih.gov/). The gene discussed is CACNA1C; the disease is schizophrenia.