Chemokines are grouped according to their different structures and functions into four families: CC, CXC, C, and CX3C. CXC chemokines are the second largest family of chemokines, and increasing evidence suggests that chemokine expression is associated with tumor angiogenesis, tumor, progression, and metastasis [13, 14, 15]. The gene discussed is CXCR1; the disease is neoplasm.