Both the tumor volume and weight were lower in the mice that received CXCL1 siRNA compared with the negative control siRNA‐treated mice (tumor volume, 603.4 ± 60.8 mm3 vs. 1095.1 ± 102.1 mm3; tumor weight, 283.5 ± 21.3 mg vs. 492.5 ± 43.1 mg, respectively). This evidence concerns the gene CXCL1 and neoplasm.