MYH11 and atherosclerosis: To study clonal VSMC proliferation in disease, we crossed Myh11-CreERt2/Rosa26-Confetti animals onto an ApoE−/− background15 and induced recombination in 6- to 8-week-old animals before feeding them an atherosclerosis-inducing high-fat diet (21% fat and 0.2% cholesterol) for 16 to 19 weeks (Figure 2A; Online Table II).