The areas under the ROC curves for initial DNI, CRP, and WBC for differentiating the ADHF group from the ADHF with pneumonia group were 0.916 (95% confidence intervals [CI] 0.859–0.955), 0.828 (95% CI 0.756–0.886), and 0.715 (95% CI 0.635–0.786), respectively. This evidence concerns the gene CRP and pneumonia.