LPS from D. desulfuricans causes secretion of proinflammatory cytokine IL-6 and neutrophils, basophils, and T-cell attracting chemokine IL-8 by human gingival fibroblast (HGF-1) cell line [85] and in human umbilical vein endothelial (HUVEC) cells [86] and IL-6 by Tamm–Horsfall protein 1 (THP1) cells [87], whereas it downregulated IL-8 secretion by Colonic adenocarcinoma (Caco-2 cells) [88]. Here, IL6 is linked to colon adenocarcinoma.