DNASE1 and cystic fibrosis: The fact that treatment with DNase I or subtilisin reduced the MBEC of colistin and that enzyme treatment with DNase I, alginate lyase or subtilisin all showed a reduction in biofilm biomass in Achromobacter biofilms paves the way for further research into using dispersal mechanisms, possibly targeting several matrix components, to improve antimicrobial treatment strategies in chronic Achromobacter infections in cystic fibrosis patients.