In humans, a number of common variants in linkage disequilibrium (LD) at the BACH2 locus have been consistently associated with autoimmune conditions, including type 1 diabetes (2), celiac disease (3, 4), autoimmune thyroid disease (5, 6), Crohn's disease (7), multiple sclerosis (8), vitiligo (9), and rheumatoid arthritis (10). This evidence concerns the gene BACH2 and type 1 diabetes mellitus.