Our results were consistent with previous meta-analysis conducted by Jin et al. [84] and Yin et al. [85] which showed that IL-10 −1082 A/G polymorphism was associated with ischaemic stroke susceptibility in Asians, not consistent with the results from the studies of Kumar et al. [86] and Jin et al. [87] which showed that IL-6 −174G/C and −572C/G polymorphisms were not be associated with an increased susceptibility to ischaemic stroke, and Ye et al. [88] which inferred that IL-1β −511C/T polymorphism might be moderately associated with increased risk of ischaemic stroke. This evidence concerns the gene IL10 and ischemic stroke.