Subgroup analysis by ethnicity showed that IL-10 −1082A/G polymorphism was significantly associated with increased the cerebral infarction risk under the allelic model (OR=0.68, 95% CI=0.46–0.99, P=0.04) and heterologous model (OR=0.74, 95% CI=0.60–0.92, P=0.006) as shown in Figure 5. This evidence concerns the gene IL10 and brain infarction.