SERPINE1 and cardiac arrest: From the first report of DIC following cardiac arrest [8], higher levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and IL-8 [4, 9, 10]; increased tissue factor levels [11]; insufficient levels of tissue factor pathway inhibitor (TFPI), antithrombin, protein C and protein S [4, 11]; and increased PAI-1 levels [12, 13] have been repeatedly confirmed during cardiopulmonary resuscitation (CPR) and after return of spontaneous circulation (ROSC).