To explore whether Hsp60 was involved in HCC cell proliferation and apoptosis, we analyzed the correlation of mRNA expression between Hsp60 and proliferation or apoptosis-related genes, such as BCL2 associated X (BAX), KI67 and Proliferating cell nuclear antigen (PCNA) using TCGA database. The gene discussed is BAX; the disease is hepatocellular carcinoma.