It is noteworthy that expression of Havcr1 and Lcn2, which encode kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) respectively, is highly upregulated in the late stage of repaired kidneys after ischemia-reperfusion injury (IRI)35. This evidence concerns the gene HAVCR1 and ischemia reperfusion injury.