Some studies have demonstrated that miR-98 has suppressive effects on oral squamous cell carcinoma [17], non-small-cell lung cancer [18], glioma [31], and melanoma [19], and plays an inhibitory role in tumor angiogenesis and invasion by inhibition of ALK4 and MMP11 [32]. The gene discussed is ACVR1B; the disease is oral cavity squamous cell carcinoma.