CPB2 and infection: However, unlike C. perfringens alpha toxin (CPA), the pathogenic role of CPB2 in the pig enteric disease caused by an infection of C. perfringens type C isolates has not been characterized yet [4, 7, 8], and its cytopathological functions and mechanisms of cytotoxicity are also currently unknown, largely owing to a difficulty in the purification of CPB2 toxin and a lack of antibodies specifically against the toxin.