In those studies, H19 expression was significantly associated with histological grade (OR = 0.50, 95% CI = 0.29–0.86, P = 0.01, fixed-effect), TNM stage (OR = 0.19, 95% CI = 0.11–0.33, P < 0.00001, fixed-effect), and tumor invasion depth (OR = 0.11, 95% CI = 0.04–0.27, P < 0.00001, fixed-effect) (Figures 3(a)–3(c)) in GC. This evidence concerns the gene H19 and gastric cancer.