WNT3 and pentalogy of Cantrell: These features are part of ‘tetra-amelia syndrome’ (TAS) which is an extremely rare autosomal recessive congenital disorder, characterized by absence of all four limbs and anomalies involving the cranium and face, urogenital system, anorectum, heart, lungs, skeleton, and central nervous system.[1] Mutation in WNT3 gene (Chromosome 17q21) has been linked to TAS.