IL6 and Splenomegaly: Interestingly, in MF, irrespective of patients being at diagnosis or not, there was a positive correlation between the plasma levels of CRT and BM fibrosis (p = 0.038; r = 0.39), splenomegaly (p = 0.0089; r = 0.47), and circulating IL-6 (p = 0.028; r = 0.42) (Figures 2(a), 2(b), and 2(c)).