IGHG3 and malaria: Overall, age, malaria specific antibody levels in cord blood and at 3 months, an infection having occurred either at the 3-month period or at the 3-to-6-month period before antibody measurement and environmental factors were significantly associated with the acquisition of antigen-specific IgG (data not shown), IgG1 and IgG3 in 6-to-18-month old infants.