POMC and small cell lung carcinoma: SCLC has distinctive neuroendocrine features [5] and is capable of secreting or co-secreting a variety of neuropeptides and neurotransmitters including acetylcholine (ACh) [6, 7], pro-opiomelanocortin (POMC), and adrenocorticotropic hormone (ACTH) [8, 9].