RBFOX2 and coronary artery disorder: Prior WES analyses identified de novo RBFOX2 LOF variants in four CHD probands (including the subject with ASE), and SGSM1 LOF variants in two CHD probands (one each de novo and inherited), but no RBFOX2 or SGSM1 LOF variant in 1,800 controls3, 4, 8.