ERBB2 and cancer: Cancer cell lines assessed were A549 lung adenocarcinoma, Raji Burkitt’s lymphoma and SKBR3 breast adenocarcinoma because chimeric or humanized antibodies that recognize specific antigens (ganglioside GM2 on A549, CD20 on Raji and HER2 on SKBR3) on their surface are either available or already in clinical use.