While FGFR1 amplifications have been found in up to 22% of squamous cell carcinomas of the lung and about 15% in head and neck cancers, we found neither FGFR1, FGFR2, nor FGFR3 amplifications by FISH in squamous differentiated bladder cancer [11, 17]. Here, FGFR2 is linked to squamous cell carcinoma.