While FGFR1 amplifications have been found in up to 22% of squamous cell carcinomas of the lung and about 15% in head and neck cancers, we found neither FGFR1, FGFR2, nor FGFR3 amplifications by FISH in squamous differentiated bladder cancer [11, 17]. The gene discussed is FGFR3; the disease is head and neck cancer.