XPC and cancer: However, we found that carriers of one or two risk XPC genotypes had similar cancer risk to those carrying two wild-type genotypes (adjusted odds ratio (OR) = 1.13, 95% confidence interval (CI) = 0.77–1.66, p = 0.524 for carriers of one risk genotype; adjusted OR = 1.03, 95% CI = 0.69–1.54, p = 0.884 for carriers of two risk genotypes) (Table 2).