There are at least four critical steps involved in the NER pathway: (a) recognition of damaged DNA via a protein complex containing xeroderma pigmentosum group C (XPC); (b) uncoiling of DNA mediated by the transcription factor II human (TFIIH) complex; (c) excision of the damaged single-stranded fragment; (d) gap-filling DNA synthesis and DNA ligation [2,3]. Here, XPC is linked to xeroderma pigmentosum.