Brentuximab vedotin (Anti-CD30, MMAE) and ado-trastuzumab emtansine (Anti-Her2/neu, maytansine) are approved by the FDA for the treatment of Hodgkin’s lymphoma and HER2 positive metastatic breast cancer, respectively [17,18,19,20]. Here, ERBB2 is linked to Hodgkins lymphoma.