The primary functional groups were tight junction, leukocyte transendothelial migration, inflammatory bowel disease (IBD), MAPKs, forkhead box O (FoxO), phosphatidylinositol 3-kinase/Akt (PI3K/Akt), Janus kinase/signal transducer, and activator of transcription (JAK/STAT) pathways, as well as apoptosis. Here, AKT1 is linked to inflammatory bowel disease.