However, the EB patients with a lower BEBS score showed significantly higher IL-1β, IL-2, IL-6, IL-10, IL-12, TNF-β and IFN-γ than did the controls (p = 0.015, p = 0.004, p = 0.004, p = 0.038, p = 0.038, p < 0.001 and p = 0.021, respectively). This evidence concerns the gene IL1B and epidermolysis bullosa.