PGF and neoplasm: On day 22, at which time the animals were sacrificed, the mean tumor mass of the Ad(sh)PlGF treated group (2045 ± 1654 mg) was significantly reduced compared to PBS treated control (5738 ± 853 mg) and AdRFP (4791 ± 1266 mg) control mice (p < 0.032; Figure 3A).