CYP24A1 and non-small cell lung carcinoma: Together with the relationships between NSCLC risk and variants in genes associated with VDR and CYP24A1, these results support the concept that NSCLC carcinogenesis may be influenced by the vitamin D axis, including the interaction between the different components of vitamin D, which includes circulating vitamin D, the CYP24A1, and the VDR. The reason why there is a discrepancy in these SNPs is unclear.