The results showed that the significant risk factors included serum CysC level (P = 0.003; OR = 4.828), the presence of CAD (P = 0.005; OR = 3.566), insulin use (P = 0.010; OR = 2.605), the differences between supine and sitting of TcPO2 (P = 0.001; OR = 1.076), and the presence of hypertension (P = 0.023; OR = 1.021). Here, INS is linked to Hypertension.