There are case reports describing the use of epidural bupivacaine infusions in male patients with BrS resulting in a Brugada-type ECG pattern [11], PVCs and ventricular fibrillation [12], and ventricular tachycardia and electrical storm in an undiagnosed Brugada patient with a SCN5A mutation [13]. This evidence concerns the gene SCN5A and ventricular fibrillation.