POZ-ICG maintained high tumor accumulation (9.4%ID/g at 24 h post-injection for P14-ICG7.8) even though large number of ICG molecules was loaded unlike ICG-conjugated HSA (HSA-ICG, ICG/HSA = 8.2) (2.1%ID/g at 24 h post-injection)11. This evidence concerns the gene ALB and neoplasm.