PPIB and atopic eczema: In an earlier study, supported by the BSF, we showed that cyclophilin B (CypB), an endoplasmic reticulum (ER)‐resident protein, is secreted by keratinocytes in response to pharmacologically relevant concentrations of ciclosporin.28 Moreover, a key residue within the ciclosporin‐binding site of CypB controlled the secretion of CypB.28 These findings may be relevant to the action of ciclosporin in atopic eczema because CypB is known to induce chemotaxis of inflammatory cells and keratinocytes themselves express CypB (CD147) receptors.