The FLG mutations were shown to be a major genetic risk factor for asthma per se, but further analysis revealed that all of the observed association was with asthma plus eczema group, where as the asthma‐only group showed no FLG association.11 This result demonstrated that there are at least two forms asthma – one driven via an eczema/skin barrier pathomechanism and the other driven by some other unknown mechanism(s). Here, FLG is linked to asthma.