Importantly, our findings were quickly and widely replicated across many studies of Caucasian AD patients and our initial publication, in March 2006, is currently the most cited paper in dermatology.11 We went on to develop techniques to re‐sequence the entire filaggrin gene and used these methods to identify common and rare mutations in many different human populations.10 These mutations were causative for IV in these other ethnic groups13 and also strongly associated with AD across many populations, establishing filaggrin as the major genetic risk factor for AD and atopy. The gene discussed is FLG; the disease is Alzheimer disease.