Such is the case of the clock genes Npas2, Gsk3β, Dbp, Cry1, and Clock that are also implicated in psychiatric diseases (Niculescu et al., 2000; Bhat and Budd, 2002; Johansson et al., 2003; Takano et al., 2004; Roybal et al., 2007; Soria et al., 2010; Geoffroy et al., 2015) as well as in other brain pathologies (Table 1). The gene discussed is CLOCK; the disease is psychiatric disorder.