TARDBP and frontotemporal dementia: TDP-43 positive cytoplasmic inclusions have also been described in 57% of Alzheimer’s disease cases, 20% of Dementia with Lewy Bodies, Pick’s disease, hippocampal sclerosis, corticobasal degeneration, Huntington disease, Parkinson’s disease, argyrophilic grain disease, and in a variety of other neurodegenerative conditions19, 20.