In addition, the expression of minor allele T in epithelial ovarian cancer cells has been related to decreased proliferation, migration, and invasion compared to common allele A. Additionally, the stable expression of HOXA11-AS minor allele T reduced the primary tumor growth in mouse xenograft models, to a greater extent, than common allele A. Besides, HOXA11-AS expression levels were considerably lower in ovarian cancer tissues compared with normal ovarian tissues, implying a tumor suppressor role for this lncRNA in ovarian cancer, which may be increased by the T allele[23]. Here, HOXA11 is linked to malignant epithelial tumor of ovary.